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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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C. Drug-Fungal Interactions:

Here are the key drug-fungal infections to be aware of:

1. Onyolic Acid Dehydrogenase Inhibitors (e.g., torsemide, sodium valdehyde): These medications are generally not prescribed for treating urinary tract infections (e.g., Stuckland). They can cause QT prolongation in patients with diabetes. They can also increase blood pressure levels, which may result in symptomatic hypotension.
2. Calcium Channel Blockers (e.g., sildenafil, tadalafil): Though not a direct interaction, combining Cialis with calcium-channel inhibitors may impair your ability to get and maintain an erection, leading to dizziness, headaches, or low blood pressure. Limiting this treatment to those requires specific dosage adjustments.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

• Headache
• Indigestion
• Heartburn
• Upset stomach
• Gas
• Nausea
• Flushing

More severe side effects include:

• Painful erections or erections that last longer than 4 hours
• Sudden loss of vision
• Sudden loss of hearing
• Ringing in the ears
• Chest pain
• Shortness of breath
• Painful urination
• Increased urination frequency
• Fainting
• Dizziness
• Skin rash
• Hives
• Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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See your doctor for checkups with your doctor before you start taking Cialis. Take note of your dosage and how you are beginning to feel. If you experience any side effects, such as dizziness, lightheadedness, heart attack, or low blood pressure, seek medical attention immediately.

As with any prescription medication, inform your doctor of any prescription-only drug products you are using, including prescription drugs, non-prescription medications, and herbal products. These products can have side effects like irregular heartbeat, dizziness, lightheadedness, and fainting.

Cialis can interact with nitrates (medicines used in blood pressure management) which should not be taken. In addition, Cialis can interact with certain blood pressure medication used for the treatment of HIV infection. These can be low blood pressure or high blood pressure because Cialis interacts with can cause dilation and loss of blood vessels.

As with all prescription medication medications, ensure your doctor knows your medical history before starting treatment with Cialis. You should also mention any conditions you were prescribed for during treatment with Cialis.

Your doctor can, at will, monitor you closely for any changes in your condition. If you experience any changes in your heart rate or chest pain during sex, they are expected to replace them with healthy heartbeats.

If you have any questions regarding Cialis, contact your doctor or pharmacist. awaits.

How long do the Cialis’s last effect?

Cialis typically begins to work within 30 minutes to 1 hour after ingestion. However, Cialis can take up to an hour to show effects. Do not take more than one dose a day.

Cialis can cause dizziness and fainting. If you experience these, contact your doctor.

Cialis can cause changes in your vision.

Cialis can cause side effects similar to those associated with nitrates (drugs prescribed for chest pain).

As with all prescription medication medications, it’s crucial to note that Cialis can interact with certain prescription drugs, including some herbal supplements. This can cause side effects that may require immediate medical attention.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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Cautions

Physical Health:

To ensure safe and effective treatment, be aware of physical health risks:

• Increased risk of cardiovascular events such as heart attack or stroke
• Low blood pressure ( hypotension)
• Strict sports medicine use (see also Medication Guide and product information)

Caution:

If you have heart disease, diabetes, high blood pressure, irregular heartbeats, or surgery that disrupts the normal blood flow of the penis, you should seek immediate medical attention or consult for a penile examination. Inform your doctor about any existing medical conditions, allergies to medications or substances, or other treatments you are taking that may possibly affect your heartbeat.

Other Drug-Food Interactions:

If you are taking or have taken an alpha-blocker, use it only as directed by your doctor. It is not recommended to take it with other medications or substances, such as alpha-blockers.

Cialis Together for Erectile Dysfunction

Cialis Together tablets are a treatment for adult men who have erection problems (erectile dysfunction). This is when a man cannot get, or keep an erection hard enough for satisfactory sexual activity.

Cialis Together tablets contain the active substance tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood flow into your penis.

It is important to know that you will not get an erection just by taking Cialis Together tablets. This medicine works with your body’s natural function to get an erection only when you are sexually stimulated.

Cialis Together contains the active ingredient Tadalafil. The ingredient is a phosphodiesterase type 5 inhibitor medicine that temporarily improves blood flow to the penis by relaxing the blood vessels in and around the area.

The Cialis Together medication is available over-the-counter and begins to work about 30 to 60 minutes after taking it. The effects are expected to last up to 36 hours. Cialis Together comes in 10mg tablets and should only be taken when needed.

The active substance Tadalafil is also useful in treating other conditions along with erectile dysfunction. Please consult a Doctor, a Pharmacist or relevant product literature for more information.

Is Cialis Together right for me?

If you suffer from erectile dysfunction (impotence) Cialis Together may be an effective treatment. However, it may not be suitable for you if you have the following:

• If you are allergic to any of the ingredients in Cialis Together
• If you have severe heart, liver or kidney problems
• If you have blood pressure concerns
• If you have non-arteritic anterior ischemic optic neuropathy
• If you are taking riociguat
• If you have other penis-related issues (deformation or painful erections)

Always read the instructions included with the Cialis Together online pharmacist.ie Prescribers list, follow the instructions for buying Cialis Together online.